Article

Aging Converts Microglial Repopulation into Maladaptive Reprogramming that Exacerbates Cognitive Deficits

2026-01-09

Abstract excerpt

<h4>Background and Purpose</h4> Aging has been associated with neuroinflammation and cognitive decline. Microglial repopulation after pharmacological depletion has been proposed as a strategy to alleviate microglia-driven neuropathology. However, the effects of microglial repopulation on age-related cognitive decline remain largely unexplored. In the present study, we examined how microglial repopulation affects...

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Literature Corpus work: 6d623a03-8586-5669-8112-8534322b9299
DOI: 10.64898/2026.01.08.698519

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