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Cellular Senescence Is a Central Driver of Cognitive Disparities in Aging

12 Mar 2025

Abstract excerpt

ABSTRACT Cognitive function in aging is heterogeneous: while some older individuals develop significant impairments and dementia, others remain resilient and retain cognitive function throughout their lifespan. The molecular mechanisms that underlie these divergent cognitive trajectories, however, remain largely unresolved. Here, we utilized a high‐resolution home‐cage‐based cognitive testing paradigm to...

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PMID: 40077862
DOI: 10.1111/acel.70041

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