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Core Activation Program and Selective Regional Responsiveness of Microglia in Aging and Parabiosis

2025-10-31

Abstract excerpt

Aging is associated with immune dysregulation in brain and is the biggest risk factor for many neurodegenerative diseases whereas rejuvenation interventions can mediate beneficial effects. Microglia are considered as a major player in the development of neurodegenerative disease yet, the molecular changes underlying brain aging and rejuvenation remain poorly understood at the single cell level. We identified and b...

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Identifiers and source

Literature Corpus work
57534f59-cc92-5f0c-a9dc-c9a222ad154e
DOI
10.1101/2025.10.29.685417
Open publication

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Core Activation Program and Selective Regional Responsiveness of Microglia in Aging and ParabiosisDOI 10.1101/2025.10.29.685417
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