Article

Microglia and infiltrating T-cells adopt long-term, age-specific, transcriptional changes after traumatic brain injury

2022-01-13

Abstract excerpt

<title>Abstract</title> <p>Introduction: Traumatic brain injury (TBI) afflicts over 3 million Americans every year. Patients over 65 years of age suffer increased mortality as well as greater long-term neurocognitive and neuropsychiatric morbidity compared to younger adults. Microglia, the resident macrophages of the brain, are complicit in both. Our published and preliminary data have demonstrated a significant...

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Literature Corpus work: 930b636e-4133-5ec5-af39-071f49a30bfa
DOI: 10.21203/rs.3.rs-1230439/v1

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