Article

Mapping the genetic regulation of long non-coding RNAs across cellular contexts advances understanding of complex brain diseases

2026-04-14

Abstract excerpt

<title>Abstract</title> <p>Long non-coding RNAs (lncRNAs) play essential roles in the pathogenesis of neurological disease, but the cellular heterogeneity of their genetic regulation remains poorly understood, with a key barrier being the resolution–power trade-off between bulk and single-nucleus eQTL studies. Here, we profiled 17,541 lncRNAs including both GENCODE-annotated and newly assembled transcripts in the...

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Literature Corpus work: 6d2bf769-c6a4-535c-b3c0-5d4c2e731ce9
DOI: 10.21203/rs.3.rs-8945185/v1

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