Article
Brain expression quantitative trait locus and network analysis reveals downstream effects and putative drivers for brain-related diseases
2021-03-02
Abstract excerpt
Gaining insight into the downstream consequences of non-coding variants is an essential step towards the identification of therapeutic targets from genome-wide association study (GWAS) findings. Here we have harmonized and integrated 8,727 RNA-seq samples with accompanying genotype data from multiple brain-regions from 14 datasets. This sample size enabled us to perform both cis - and trans -expression quantitat...
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Identifiers and source
- Literature Corpus work
- 061b195c-03ee-5299-b8d4-b339086c1c10
- DOI
- 10.1101/2021.03.01.433439