Article

Epigenetic Control of Hundreds of Chromosome-Associated lncRNA Genes Essential for Replication and Stability

2022-04-25

Abstract excerpt

ASARs are long noncoding RNA genes that control replication timing of entire human chromosomes in cis . The three known ASAR genes are located on human chromosomes 6 and 15, and are essential for chromosome integrity. To identify ASARs on all human chromosomes we utilized a set of distinctive ASAR characteristics that allowed for the identification of hundreds of autosomal loci with epigenetically controlled, all...

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Literature Corpus work: 6d21c9c1-49d3-59a0-aad4-8a8ca1b8840e
DOI: 10.1101/2022.04.25.489405

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