Article

Reciprocal monoallelic expression of ASAR lncRNA genes controls replication timing of human chromosome 6

2019-08-12

Abstract excerpt

<h4> Abstract </h4> DNA replication occurs on mammalian chromosomes in a cell-type distinctive temporal order known as the replication timing program. We previously found that disruption of the noncanonical lncRNA genes ASAR6 and ASAR15 results in delayed replication timing and delayed mitotic chromosome condensation of human chromosome 6 and 15, respectively. ASAR6 and ASAR15 display random monoallelic expr...

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Literature Corpus work: 77b7056e-c90d-529e-aabc-155d83ebc2d1
DOI: 10.1101/732784

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