Article

Consistent Genes Associated With Structural Changes in Clinical Alzheimer’s Disease Spectrum

2021-09-21

Abstract excerpt

<h4>Background: </h4> Previous studies showed no obvious symptoms but subtle structural brain changes in a long preclinical stage of Alzheimer's disease (AD), then localized cortical and sub-cortical atrophy in MCI, and spread aggressively to nearly whole brain neurodegeneration in AD. However, the neurobiological and pathogenic substrates underlying these structural changes across AD spectrum remain largely under...

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Literature Corpus work: 4fa5da7e-da5e-51ba-97be-325fff208efb
DOI: 10.21203/rs.3.rs-903119/v1

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