Article

The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking

2022-12-02

Abstract excerpt

Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well established that post-transcriptional regulation plays a significant role in EMT, the extent of alternative polyadenylation (APA) during EMT has not yet been explored. Using 3’ end anchored RNA sequencing, we mapped the alternative polyadenylation landscape...

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Literature Corpus work: 6bf20f5d-9c5b-5c4d-a00e-92f89818b04c
DOI: 10.1101/2022.12.01.518773

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