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Characterization of Immune-Related Alternative Polyadenylation Events in Cancer Immunotherapy

5 Aug 2022

Abstract excerpt

Alternative polyadenylation (APA) is an important posttranscriptional modification commonly involved in tumor development. However, the functional roles of APA in tumor immunity remain largely unknown. Here, we performed an in-depth analysis of the 3'UTR usage of protein-coding genes and tumor immune response in 10,303 tumor samples across 31 cancer types to develop the immune-related APA event (ImmAPA) score...

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PMID: 35930727
DOI: 10.1158/0008-5472.can-22-1417

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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