Article

METTL3 regulates breast cancer-associated alternative splicing switches

2022-04-11

Abstract excerpt

<h4>ABSTRACT</h4> Alternative splicing (AS) enables differential inclusion of exons from a given transcript, thereby contributing to the transcriptome and proteome diversity. Aberrant AS patterns play major roles in the development of different pathologies, including breast cancer. N 6 -methyladenosine (m 6 A), the most abundant internal modification of eukaryotic mRNA, influences tumor progression and metastas...

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Literature Corpus work: 0f2b993e-c07f-5c53-ad3f-817a691f56cd
DOI: 10.1101/2022.04.11.487899

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