Article

Fate mapping via Ms4a3 expression history traces monocyte-derived cells

2019-05-27

Abstract excerpt

<h4>SUMMARY</h4> Most tissue-resident macrophage (RTM) populations are seeded by waves of embryonic hematopoiesis and are self-maintained independently of a bone-marrow contribution during adulthood. A proportion of RTMs, however, is constantly replaced by blood monocytes and their functions compared to embryonic RTM remains unclear. The kinetics and extent of the contribution of circulating monocytes to RTM repl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6b948005-30bf-52b2-8864-85487d500e09
DOI: 10.1101/652032

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Fate mapping via Ms4a3 expression history traces monocyte-derived cellsDOI 10.1101/652032Read

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C- Cells.Semantic proximity Read

Genetic Mapping of Monocyte Fate Decisions Following Myocardial InfarctionSemantic proximity Read

Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors.Semantic proximity Read

Ly6C <sup>hi</sup> monocytes are metabolically reprogrammed in the blood during inflammatory stimulation allowing for macrophage lineage commitmentSemantic proximity Read

Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risksSemantic proximity Read

Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous SystemSemantic proximity Read

Path of differentiation defines human macrophage identitySemantic proximity Read

Cellular reprogramming of human monocytes is regulated by time-dependent IL4 signalling and NCOR2Semantic proximity Read

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responsesSemantic proximity Read

Monocyte Single-Cell Multimodal Profiling in Cardiovascular Disease Risk StatesSemantic proximity Read

Understanding macrophage diversity at the ontogenic and transcriptomic levels.Semantic proximity Read

Robust temporal map of human <i>in vitro</i> myelopoiesis using single-cell genomicsSemantic proximity Read