Article

Ly6C <sup>hi</sup> monocytes are metabolically reprogrammed in the blood during inflammatory stimulation allowing for macrophage lineage commitment

2021-11-15

Abstract excerpt

Acute inflammation is a rapid and dynamic process involving the recruitment and activation of multiple cell types in a co-ordinated and precise manner. Using cell tracking, linage tracing and single cell transcriptomics we investigated the origin and transcriptional reprogramming of monocytes and macrophages in acute inflammation. Monocyte trafficking and adoptive transfer experiments revealed that monocytes under...

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Literature Corpus work: b1cf1fe3-e9d6-57c6-a0d3-c9692ee869ac
DOI: 10.1101/2021.11.15.468584

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