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Monocyte Single-Cell Multimodal Profiling in Cardiovascular Disease Risk States

6 Aug 2024

Abstract excerpt

BACKGROUND: Monocytes are a critical innate immune system cell type that serves homeostatic and immunoregulatory functions. They have been identified historically by the cell surface expression of CD14 and CD16. However, recent single-cell studies have revealed that they are much more heterogeneous than previously realized. METHODS: We utilized cellular indexing of transcriptomes and epitopes by sequencing...

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PMID: 39105287
DOI: 10.1161/circresaha.124.324457

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