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Article

Cellular reprogramming of human monocytes is regulated by time-dependent IL4 signalling and NCOR2

2017-10-16

Abstract excerpt

The clinical and therapeutic value of human in vitro generated monocyte-derived dendritic cell (moDC) and macrophages is well established. However, in line with recent findings regarding myeloid cell ontogeny and due to our limited understanding of their physiological counterparts, transcriptional regulation and heterogeneity, the full potential of these important cellular systems is still underestimated. In thi...

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Literature Corpus work
706b748b-bf46-5003-966c-62955aa09dd9
DOI
10.1101/204180
Open publication

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Cellular reprogramming of human monocytes is regulated by time-dependent IL4 signalling and NCOR2DOI 10.1101/204180
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