Article

Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks

2024-02-21

Abstract excerpt

Monocytes are a critical innate immune system cell type that serves homeostatic and immunoregulatory functions. The Cell surface expression of CD14 and CD16 has historically identified them, however, recent single-cell studies have uncovered that they are much more heterogeneous than previously realized. We utilized cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) and single-cell RNA seque...

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Literature Corpus work: 8c4bd389-2d10-53a2-a00b-fd359b768b17
DOI: 10.1101/2024.02.18.580913

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