Article
Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors.
Immunity - 8 Aug 2023
Liu Zhaoyuan, Wang Haiting, Li Ziyi, Dress Regine J, Zhu Yiwen, Zhang Shuangyan, De Feo Donatella, Kong Wan Ting, Cai Peiliang, Shin Amanda, Piot Cécile, Yu Jiangyan, Gu Yaqi, Zhang Mingnan, Gao Caixia, Chen Lei, Wang Honglin, Vétillard Mathias, Guermonprez Pierre, Kwok Immanuel, Ng Lai Guan, Chakarov Svetoslav, Schlitzer Andreas, Becher Burkhard, Dutertre Charles-Antoine, Su Bing, Ginhoux Florent
Abstract excerpt
Conventional dendritic cells (cDCs) are professional antigen-presenting cells that control the adaptive immune response. Their subsets and developmental origins have been intensively investigated but are still not fully understood as their phenotypes, especially in the DC2 lineage and the recently described human DC3s, overlap with monocytes. Here, using LEGENDScreen to profile DC vs. monocyte lineages, we found...
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