Article

Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation

2025-05-29

Abstract excerpt

<h4>SUMMARY</h4> Hematopoietic stem and progenitor cells (HSPC) respond to infections, inflammation, and regenerative challenges using a collection of cellular and molecular mechanisms termed emergency myelopoiesis (EM) pathways. However, it remains unclear how various EM inducers regulate HSPCs using shared or distinct molecular mechanisms. Here, we generate a comprehensive and generalizable cell annotation meth...

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Literature Corpus work: 6b7d2431-2c93-594f-99e2-f4e130abaa13
DOI: 10.1101/2025.05.28.656712

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