Article

Abnormal nitration and S-sulfhydration of Sp1-CSE-H <sub>2</sub> S pathway contribute to the progress of hyperhomocysteinemia: a vicious circle

2019-11-19

Abstract excerpt

<h4>ABSTRACT</h4> Sp1 (Specificity protein 1)-CSE (cystathionine-γ-lyase)-H 2 S (hydrogen sulfide) pathway plays an important role in homocysteine-metabolism, whose disorder can result in hyperhomocysteinemia. The deficiency of plasma H 2 S in patients and animal models with hyperhomocysteinemia has been reported but it is unclear whether this deficiency plays a role in the progress of hyperhomocysteinemia. Fur...

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Literature Corpus work: 6b66c338-610f-58f2-9527-6c0efef7765d
DOI: 10.1101/843854

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