Article
Interaction between hydrogen sulfide-induced sulfhydration and tyrosine nitration in the KATP channel complex.
American journal of physiology. Gastrointestinal and liver physiology - 15 Mar 2015
Kang Minho, Hashimoto Atsushi, Gade Aravind, Akbarali Hamid I
Abstract excerpt
Hydrogen sulfide (H₂S) is an endogenous gaseous mediator affecting many physiological and pathophysiological conditions. Enhanced expression of H2S and reactive nitrogen/oxygen species (RNS/ROS) during inflammation alters cellular excitability via modulation of ion channel function. Sulfhydration of cysteine residues and tyrosine nitration are the posttranslational modifications induced by H₂S and RNS,...
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