Article
Regulation of cystathionine gamma-lyase/H₂S system and its pathological implication.
Frontiers in bioscience (Landmark edition) - 1 Jun 2014
Zhao Kexin, Li Hongzhu, Li Shuangshuang, Yang Guangdong
Abstract excerpt
Hydrogen sulfide (H2S) is a highly diffusible gasotransmitter, that influence cellular and organ functions by a number of different mechanisms. Cystathionine gamma-lyase (CSE) is one major H2S-producing enzyme with L-cysteine as the main substrate in mammalian cells. Since the discovery of endogenously-produced H2S as a biological mediator, there has been an explosion of interest in CSE expression and regulation....
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