Article

Conditional disruption of AMP kinase in dopaminergic neurons promotes Parkinson’s disease-associated phenotypes in mice

2020-07-27

Abstract excerpt

<title>Abstract</title> <p>Emerging studies implicate energy dysregulation as an underlying trigger for Parkinson’s disease (PD), suggesting that a better understanding of the molecular pathways governing energy homeostasis could help elucidate therapeutic targets for the disease. A critical cellular energy regulator is AMP kinase (AMPK), which we have previously shown to be protective in PD. However, precisely h...

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Literature Corpus work: 6a93579b-9889-550d-9358-439d4fb22971
DOI: 10.21203/rs.3.rs-43593/v1

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