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Article

Mitochondrial dysfunction and Parkinson disease: a Parkin-AMPK alliance in neuroprotection.

Annals of the New York Academy of Sciences - 1 Sept 2015

Hang Liting, Thundyil John, Lim Kah-Leong

Abstract excerpt

Although a subject of intense research, the etiology of Parkinson disease (PD) remains poorly understood. However, a wide range of studies conducted over the past few decades have collectively implicated aberrant mitochondrial homeostasis as a key contributor to the development of PD. Particularly strong support for this came from the recent demonstration that parkin, a familial PD-linked gene, is a critical...

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Identifiers

PMID: 26121488
DOI: 10.1111/nyas.12820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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