Article

CTCF-mediated insulation and chromatin environment modulate <i>Car5b</i> escape from X inactivation

2023-05-04

Abstract excerpt

<h4>Background</h4> The number and escape levels of genes that escape X chromosome inactivation (XCI) in female somatic cells vary among tissues and cell types, potentially contributing to specific sex differences. Here we investigate the role of CTCF, a master chromatin conformation regulator, in regulating escape from XCI. CTCF binding profiles and epigenetic features were systematically examined at constitutiv...

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Literature Corpus work: 6a15b1f4-4a2c-5dc8-adaa-29f026c31e8b
DOI: 10.1101/2023.05.04.539469

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