Article

Dissecting cancer resistance to therapies with cell-type-specific dynamic logic models

2016-12-16

Abstract excerpt

Therapies targeting specific molecular processes, in particular kinases, are major strategies to treat cancer. Genomic features are commonly used as biomarkers for drug sensitivity, but our ability to stratify patients based on these features is still limited. As response to kinase inhibitors is a dynamic process affecting largely signal transduction, we investigated the association between cell-specific dynamic s...

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Identifiers and source

Literature Corpus work: 695e5205-9ffa-562f-992a-d129edbefaae
DOI: 10.1101/094755

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