Article
Personalized logical models to investigate cancer response to BRAF treatments in melanomas and colorectal cancers
2020-05-27
Abstract excerpt
The study of response to cancer treatments has benefited greatly from the contribution of different omics data but their interpretation is sometimes difficult. Some mathematical models based on prior biological knowledge of signalling pathways, facilitate this interpretation but often require fitting of their parameters using perturbation data. We propose a more qualitative mechanistic approach, based on logical f...
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Identifiers and source
- Literature Corpus work
- 76a12e8b-0487-5118-8435-1a04b651e00e
- DOI
- 10.1101/2020.05.27.119016