Article

Deciphering the Signaling Network Landscape of Breast Cancer Improves Drug Sensitivity Prediction

2020-01-21

Abstract excerpt

<h4>ABSTRACT</h4> Although genetic and epigenetic abnormalities in breast cancer have been extensively studied, it remains difficult to identify those patients who will respond to particular therapies. This is due in part to our lack of understanding of how the variability of cellular signaling affects drug sensitivity. Here, we used mass cytometry to characterize the single-cell signaling landscapes of 62 breast...

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Literature Corpus work: 05f7baae-51fe-58c1-b342-688055d35537
DOI: 10.1101/2020.01.21.907691

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