Article

GWAS highlights the neuronal contribution to multiple sclerosis susceptibility

2024-12-05

Abstract excerpt

Multiple Sclerosis (MS) is a chronic inflammatory and neurodegenerative disease affecting the brain and spinal cord. Genetic studies have identified many risk loci, that were thought to primarily impact immune cells and microglia. Here, we performed a multi-ancestry genome- wide association study with 20,831 MS and 729,220 control participants, identifying 236 susceptibility variants outside the Major Histocompati...

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Literature Corpus work: 692065bf-31d2-5ad2-8c57-db7fb80532ef
DOI: 10.1101/2024.12.04.24318500

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