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Article

The genetic architecture of multiple sclerosis in 2026: From susceptibility to disease progression.

Revue neurologique - 1 May 2026

Bourguiba-Hachemi S, Paris J, Gourraud P-A, Vince N

Abstract excerpt

The genetics of multiple sclerosis (MS) has advanced dramatically through the combined impact of high-throughput genotyping, large biobank resources, worldwide collaborations, and powerful computational analyses. Over the past two decades, genome-wide association studies (GWAS) have significantly reshaped our understanding of the genetic architecture of complex multifactorial diseases such as MS. The number of MS...

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Source

Identifiers

PMID: 41934071
DOI: 10.1016/j.neurol.2026.03.006

Genes

CYP27B1
NLRP1
PRF1

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