Article
The Genetics of Multiple Sclerosis: From 0 to 200 in 50 Years.
Trends in genetics : TIG - 1 Dec 2017
Baranzini Sergio E, Oksenberg Jorge R
Abstract excerpt
Multiple sclerosis (MS) is a common autoimmune disease that targets myelin in the central nervous system (CNS). Multiple genome-wide association studies (GWAS) over the past 10 years have uncovered more than 200 loci that independently contribute to disease pathogenesis. As with many other complex diseases, risk of developing MS is driven by multiple common variants whose biological effects are not immediately...
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