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Article

Multiple sclerosis genetics--is the glass half full, or half empty?

Nature reviews. Neurology - 1 Aug 2010

Oksenberg Jorge R, Baranzini Sergio E

Abstract excerpt

Multiple sclerosis (MS) is a common and severe CNS disorder that is characterized by myelin loss, chronic inflammation, axonal and oligodendrocyte pathology, and progressive neurological dysfunction. Extensive epidemiological data confirm that genetic variation is an important determinant of susceptibility to MS, and suggest that such variation also influences the timing of symptom onset, the course of the...

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PMID: 20625377
DOI: 10.1038/nrneurol.2010.91

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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