Article

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

2017-07-13

Abstract excerpt

<h4>Abstract:</h4> We assembled and analyzed genetic data of 47,351 multiple sclerosis (MS) subjects and 68,284 control subjects and establish a reference map of the genetic architecture of MS that includes 200 autosomal susceptibility variants outside the major histocompatibility complex (MHC), one chromosome X variant, and 32 independent associations within the extended MHC. We used an ensemble of methods to pr...

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Literature Corpus work: 30faefe5-635b-5348-a501-be68ca14e719
DOI: 10.1101/143933

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