Article

Interrogation of human hematopoiesis at single-cell and single-variant resolution

2018-01-28

Abstract excerpt

Incomplete annotation of cell-to-cell state variance and widespread linkage disequilibrium in the human genome represent significant challenges to elucidating mechanisms of trait-associated genetic variation. Here, using data from the UK Biobank, we perform genetic fine-mapping for 16 blood cell traits to quantify posterior probabilities of association while allowing for multiple independent signals per region. We...

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Literature Corpus work: 687b6377-9872-5d9b-a683-a5d5f8dc6f6b
DOI: 10.1101/255224

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