Article

Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation

2017-02-21

Abstract excerpt

Normal human hematopoiesis involves cellular differentiation of multipotent cells into progressively more lineage-restricted states. While epigenomic landscapes of this process have been explored in immunophenotypically-defined populations, the single-cell regulatory variation that defines hematopoietic differentiation has been hidden by ensemble averaging. We generated single-cell chromatin accessibility landscap...

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Literature Corpus work: 2fb4b871-45ae-54bf-bf55-89ba186147b9
DOI: 10.1101/109843

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