Article

Multi-tissue transcriptome-wide association studies

2020-07-14

Abstract excerpt

Many genetic mutations affecting phenotypes are presumed to do so via altering gene expression in particular cells or tissues, but identifying the specific genes involved has been challenging. A transcriptome-wide association study (TWAS) attempts to identify disease associated genes by first learning a predictive model on an eQTL dataset and then imputing gene expression levels into a larger genome-wide associati...

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Literature Corpus work: 68475648-7eff-56fd-8e61-e81633fe126d
DOI: 10.1101/2020.07.13.201111

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