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Article

Subset-based method for cross-tissue transcriptome-wide association studies improves power and interpretability.

HGG advances - 11 Apr 2024

Guo Xinyu, Chatterjee Nilanjan, Dutta Diptavo

Abstract excerpt

Integrating results from genome-wide association studies (GWASs) and studies of molecular phenotypes such as gene expressions can improve our understanding of the biological functions of trait-associated variants and can help prioritize candidate genes for downstream analysis. Using reference expression quantitative trait locus (eQTL) studies, several methods have been proposed to identify gene-trait...

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PMID: 38491773
DOI: 10.1016/j.xhgg.2024.100283
PMCID: PMC10999697

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