Article

A statistical framework for cross-tissue transcriptome-wide association analysis

2018-03-21

Abstract excerpt

Transcriptome-wide association analysis is a powerful approach to studying the genetic architecture of complex traits. A key component of this approach is to build a model to predict (impute) gene expression levels from genotypes from samples with matched genotypes and expression levels in a specific tissue. However, it is challenging to develop robust and accurate imputation models with limited sample sizes for a...

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Literature Corpus work: b04c0581-dc82-5480-ad9e-0ced0f385a6f
DOI: 10.1101/286013

Open publication

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