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Article

Multi-tissue transcriptome-wide association studies.

Genetic epidemiology - 1 Apr 2021

Grinberg Nastasiya F, Wallace Chris

Abstract excerpt

A transcriptome-wide association study (TWAS) attempts to identify disease associated genes by imputing gene expression into a genome-wide association study (GWAS) using an expression quantitative trait loci (eQTL) data set and then testing for associations with a trait of interest. Regulatory processes may be shared across related tissues and one natural extension of TWAS is harnessing cross-tissue correlation...

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Identifiers

PMID: 33369784
DOI: 10.1002/gepi.22374
PMCID: PMC8048510

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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