Article

A Translational Model of MASLD-Associated HFpEF Defines Mitochondrial Dysfunction and Cardiac Plasticity During Disease Progression and Regression

2026-02-28

Abstract excerpt

<h4>ABSTRACT</h4> Metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH), are strongly linked to cardiac dysfunction, particularly, heart failure with preserved ejection fraction (HFpEF), yet the mechanisms underlying this association remain unclear because robust integrative preclinical models are lacking and the liver an...

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Literature Corpus work: e7bbfba2-82e7-5df1-85cc-97022c8ece8b
DOI: 10.64898/2026.02.26.708088

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