Article

TCGA <sub>DEPMAP</sub> – Mapping Translational Dependencies and Synthetic Lethalities within The Cancer Genome Atlas

2022-03-27

Abstract excerpt

<h4>ABSTRACT</h4> The Cancer Genome Atlas (TCGA) has yielded unprecedented genetic and molecular characterization of the cancer genome, yet the functional consequences and patient-relevance of many putative cancer drivers remain undefined. TCGA DEPMAP is the first hybrid map of translational tumor dependencies that was built from machine learning of gene essentiality in the Cancer Dependency Map (DEPMAP) and the...

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Literature Corpus work: 67f2b266-0e3e-56ec-a775-eaa3b0cfc690
DOI: 10.1101/2022.03.24.485544

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