Article

Modeling cancer dependency with deep graph models

2024-02-28

Abstract excerpt

A fundamental premise for precision oncology is a catalog of diverse actionable targets that could enable personalized treatment. Large scale Genome-wide lost-of-function screens such as cancer dependency map have systematically identified single gene vulnerabilities in numerous cell lines. However, it remains challenging to scale such analyses to many clinical samples and untangle molecular networks underlying ob...

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Literature Corpus work: c80b364c-cc82-5005-bfee-03d6be0c582e
DOI: 10.1101/2024.02.26.582022

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