Article

Integrative identification of non-coding regulatory regions driving metastatic prostate cancer

2023-04-16

Abstract excerpt

Large-scale sequencing efforts of thousands of tumor samples have been undertaken to understand the mutational landscape of the coding genome. However, the vast majority of germline and somatic variants occur within non-coding portions of the genome. These genomic regions do not directly encode for specific proteins, but can play key roles in cancer progression, for example by driving aberrant gene expression cont...

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Literature Corpus work: 667246f5-6499-5515-9219-30951e192136
DOI: 10.1101/2023.04.14.535921

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