Article

A programmable mRNA platform for miRNA detection via miRNA-mRNA <sub>2</sub> triplex-mediated ribosomal frameshifting

2025-11-24

Abstract excerpt

<h4>ABSTRACT</h4> Programmed −1 ribosomal frameshifting (−1 PRF) is a recoding mechanism utilized by viruses to expand their coding capacity and modulate the stoichiometric ratio of −1 frame and 0 frame translation products. The stability of mRNA secondary structure at the ribosomal entry site within the frameshifting stimulating elements (FSEs) determines the frameshifting efficiency. Here, we report the develop...

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Literature Corpus work: 66336b8b-eb44-5188-8ff6-d132e6095f0b
DOI: 10.1101/2025.11.24.690164

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