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Article

High-throughput interrogation of programmed ribosomal frameshifting in human cells

2018-11-14

Abstract excerpt

<h4>Summary</h4> Programmed ribosomal frameshifting is the controlled slippage of the translating ribosome to an alternative frame. This tightly regulated process is widely employed by human viruses such as HIV and SARS coronavirus and is critical for their life cycle and virulence. It is also utilized from yeast to human to implement a feedback control mechanism to regulate polyamine levels. Here, we developed a...

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Literature Corpus work
fd3a4d71-ef66-5d6b-a7ec-3b145e7eeeb0
DOI
10.1101/469692
Open publication

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High-throughput interrogation of programmed ribosomal frameshifting in human cellsDOI 10.1101/469692
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