Article
The translational landscape of HIV-1 infected cells reveals novel gene regulatory principles
2023-10-05
Abstract excerpt
<title>Abstract</title> <p>Human Immunodeficiency Virus-1 (HIV-1) uses a number of strategies to modulate viral and host gene expression during its lifecycle. To characterize the transcriptional and translational landscape of HIV-1 infected cells, we used a combination of ribosome profiling, disome sequencing and RNA sequencing. We found that the initial host response to viral infection is translationally regulat...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 9c491760-20f1-5765-873a-07ba09e23bc8
- DOI
- 10.21203/rs.3.rs-3352709/v1