Article

GAPDH nuclear signaling regulates neutrophil migration and inflammatory skin responses

2026-08-11

Abstract excerpt

<title>Abstract</title> <p>Neutrophils are the most abundant leukocytes and key regulators of tissue homeostasis and disease. Here we show that inhibiting Gapdh nuclear translocation limits neutrophil infiltration into inflamed skin, reduces their motility, and decreases keratinocyte hyperproliferation and cell death in a zebrafish model of skin inflammation. Wild-type Gapdh expression in neutrophils, but not a n...

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Identifiers and source

Literature Corpus work: 662fe2cc-8772-5e96-a2cc-8b6d35d4eb41
DOI: 10.21203/rs.3.rs-6170527/v1

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