Article

Aging and interferon gamma response drive the phenotype of neutrophils in the inflamed joint

2021-11-18

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> Neutrophils are typically the most abundant leukocyte in arthritic synovial fluid. We sought to understand changes that occur in neutrophils as they migrate from blood to joint. <h4>Methods</h4> We performed RNA sequencing of neutrophils from healthy human blood, arthritic blood, and arthritic synovial fluid, comparing transcriptional signatures with those from murine K/BxN...

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Literature Corpus work: 29b12655-b9b3-51ed-85de-dc4426db7a52
DOI: 10.1101/2021.11.16.465905

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