Article

Chromatin Changes Associated with Neutrophil Extracellular Trap (NET) Formation in Whole Blood Reflect Complex Immune Signaling

2025-01-04

Abstract excerpt

<h4>Background</h4> Neutrophils are key players in innate immunity, forming neutrophil extracellular traps (NETs) to defend against infections. However, excess NET formation is implicated in inflammatory conditions such as sepsis and immunothrombosis. Studying NET formation in isolated neutrophils provides important mechanistic insights but does not reflect the complexity of immune interactions in whole blood, li...

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Literature Corpus work: 99f4a860-e169-532d-b7fe-bbdf71c7c82d
DOI: 10.1101/2025.01.04.631302

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