Article

Positionally distinct interferon stimulated dermal immune acting fibroblasts promote neutrophil recruitment in Sweet’s syndrome

2024-06-28

Abstract excerpt

Sweet’s syndrome is a poorly understood inflammatory skin disease characterized by neutrophil infiltration to the dermis. Single-nucleus and bulk transcriptomics of archival clinical samples of Sweet’s syndrome revealed a prominent interferon signature in Sweet’s syndrome skin that was reduced in tissue from other neutrophilic dermatoses. This signature was observed in different subsets of cells, including fibrobl...

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Identifiers and source

Literature Corpus work: 524af2dd-d558-5fbc-a8b4-3d3142630fba
DOI: 10.1101/2024.06.24.600500

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